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. Author manuscript; available in PMC: 2010 Jun 5.
Published in final edited form as: Circulation. 2008 Feb 19;117(9):1207–1215. doi: 10.1161/CIRCULATIONAHA.107.736447

Figure 5.

Figure 5

Allelic effects of the QTL on perfusion ratio (A) and necrosis (B) at SNP marker rs13479513. The heterozygous animals (n=50) with 1 C57BL/6 and 1 BALB/c allele have higher mean of perfusion ratio and lower mean of necrosis than homozygous BALB/c animals (n=55) (0.72 vs 0.48 and 0.37 vs 1.60, respectively), indicating that the heterozygotes show more robust recovery phenotypes after hindlimb ischemia. Each bar represents mean±SEM. *P<0.001. C, Necrosis score negatively correlates with perfusion at day 21 in the N2 progeny used for mapping. Statistics was performed by Spearman rank order correlation coefficient, resulting in r=−0.628 and P<0.001.

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