Figure 1.

CD4⁺ T cell responses to peptides derived from cetuximab (black squares) and humanized cetuximab (open circles) V regions. 15-mer peptides overlapping by 12 amino acids describing the VH and VL regions of cetuximab were tested for their ability to induce proliferative responses with CD4⁺ Tcells and dendritic cells from 87 community donors. peptides derived from humanized cetuximab were tested with 106 community donors.