Skip to main content
. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Photochem Photobiol B. 2010 Mar 21;99(3):117–125. doi: 10.1016/j.jphotobiol.2010.03.005

Figure 5. Selected pathways leading to respiratory deficiency in C. glabrata contribute to increased susceptibility to PDT.

Figure 5

To better reveal differences in sensitivity to PDT among the strains, organisms were adjusted to 107 cells/ml, incubated with a range of concentrations (0.5 – 2.0 μg/ml) of TMP-1363 for 10 min and irradiated with a fluence of 2.4 J/cm2 broadband visible light (Irradiated). Organisms treated with TMP-1363 but shielded from light were used as controls (Shielded). Organism killing was determined by spotting 2 μl of ten-fold serial dilutions of treated cell suspensions on YPDextrose plates, followed by incubation at 37°C for 24 h. Representative results are shown. Abbreviations: RC (respiratory-competent); RD (respiratory-deficient).