Table 1.

Computation times for pre-processing and predictions for the nucleotide dataset

Pre-processing	Prediction of interaction hotspots	Building ligand conformations
1304 s/5524 complexes	78 s/complex	1843 s/complex

The values for the prediction of interaction hotspots and building ligand conformations are the mean values among 644 entries in the nucleotide dataset. The calculations were performed with an Intel Quad Core Xeon E5450 (3.0 GHz).