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. Author manuscript; available in PMC: 2010 Jun 7.
Published in final edited form as: J Immunol. 2010 Jan 25;184(5):2394–2400. doi: 10.4049/jimmunol.0803664

FIGURE 6.

FIGURE 6

Tregs from tolerant recipients transfer IAb-induced tolerance to B6 heart grafts. CD4+CD25− and CD4+CD25+ T cells were purified from naive CBA mice, CBA mice infused with a donor-specific transfusion (CBA+DST), or long-term tolerant IAb-CBA mice treated with DST (IAb-CBA+DST). Each T cell subset was injected separately into naive CBA mice that also received a dose of anti-CD8 mAb and B6 heart grafts on the following day. The effects of adoptive transfer of CD4+CD25− (white columns) and CD4+CD25+ (gray columns) T cells on graft survival were monitored. Each point represents survival data from a single mouse. *Survival time (days; mean ± SD).