Table 1.
Characteristics of Participants According to Childhood Maltreatment
| No/Minimal Maltreatment N = 91 | Moderate/Severe Maltreatment N = 38 | P value | |
|---|---|---|---|
| Age, Mean (SD) | 26.7 (8.78) | 35.9 (11.65) | < 0.001 |
| Range | 18-61 | 19-58 | |
| Sex, N (%) | |||
| Male | 40 (44.0) | 11 (28.9) | |
| Female | 51 (56.0) | 27 (71.1) | ns |
| BMI, Mean (SD) | 25.1 (3.3) | 27.0 (5.1) | < 0.05 |
| Range | 20.1-34.8 | 19.4-40.8 | |
| Genotype, N (%) | |||
| SNP rs242924 (N=126) | |||
| GG | 27 (30.3) | 11 (29.7) | |
| GT | 46 (51.7) | 19 (51.4) | ns |
| TT | 16 (18.0) | 7 (18.9) | |
| SNP rs110402 (N=119) | |||
| GG | 22 (26.8) | 10 (27.0) | |
| AG | 44 (53.7) | 20 (54.1) | |
| AA | 16 (19.5) | 7 (18.9) | ns |
| Type of Maltreatment, N (%)* | |||
| Emotional abuse | 0 | 19 (50.0) | — |
| Physical abuse | 0 | 8 (21.1) | — |
| Sexual abuse | 0 | 17 (44.7) | — |
| Emotional neglect | 0 | 21 (55.3) | — |
| Physical neglect | 0 | 14 (36.8) | — |
| SCID "Probable" Lifetime Axis I | |||
| Diagnoses, N (%) | |||
| Major Depressive Episode | 14 (15.4) | 12 (31.6) | < 0.05 |
| Dysthymic Disorder | 2 (2.2) | 3 (7.9) | ns |
| Alcohol Abuse/Dependence | 7 (7.7) | 8 (21.1) | < 0.05 |
| Drug Abuse/Dependence | 6 (6.6) | 3 (7.9) | ns |
| Post-traumatic Stress Disorder | 1 (1.1) | 2 (5.3) | ns |
| Panic Disorder or Social Phobia | 1 (1.1) | 2 (5.3) | ns |
Note: Percentages for types of maltreatment do not sum to 100% because participants could report more than one type of maltreatment. "ns" designates p values that are not significant. Subjects were excluded if they met the criteria for lifetime psychotic disorder or bipolar disorder, or current alcohol or drug abuse or dependence, major depression, and post-traumatic stress disorder. No participant had a lifetime diagnosis of generalized anxiety disorder.