Table 1.

Baseline Characteristics of Placebo and tPA-Treated Patients Stratified by 90-Minute Treatment Time-Windows

Variable	Time Window, Minutes	Placebo	tPA
Age	0–90	66±12	68±11
	91–180	66±12	67±11
	181–270	66±11	65±12
	271–360	65±12	66±11
Female	0–90	42.7%	38.5%
	91–180	39.0%	41.1%
	181–270	35.0%	42.8%
	271–360	41.7%	40.7%
National Institutes of Health Stroke Scale score	0–90	15 (10–19)	15 (10–20)
	91–180	13 (9–19)	11.5 (7–18)*
	181–270	12 (8–16)	11 (8–16)
	271–360	10 (7–14)	10 (7–16)
Glucose, mg/dL	0–90	142±73	150±78
	91–180	149±73	141±61
	181–270	139±57	146±60
	271–360	140±60	141±67
History of stroke	0–90	10.7%	9.9%
	91–180	13.7%	15.6%
	181–270	16.8%	15.6%
	271–360	17.7%	18.2%
History of diabetes mellitus	0–90	16.7%	21.1%
	91–180	20.0%	20.9%
	181–270	17.8%	19.2%
	271–360	19.9%	18.6%

Values are means and SD for age and glucose and medians and interquartile range for National Institutes of Health Stroke Scale score.

^*P=0.009 (2-sided Mann–Whitney U test, normal approximation).