Table 2.
Inhibitory activities of mushroom tyrosinase and DOPA auto-oxidation by different extracts of H. globosa
| Sample | % Inhibition of DOPA auto-oxidation (%) at 20 μg/ml | Inhibition of DOPA auto-oxidation (%) at 200 μg/ml | Inhibition of tyrosinase (%) at 20 μg/ml | Inhibition of tyrosinase (%) at 200 μg/ml |
|---|---|---|---|---|
| F.E | 15.7 ± 0.03 | 31.7 ± 0.05 | 13 ± 0.01 | 90.4 ± 0.03 |
| F.DC | 15.5 ± 0.02 | 19.1 ± 0.09 | 0 | 1.8 ± 0.02 |
| L.E | 0 | 8.4 ± 0.06 | 4.8 ± 0.04 | 87 ± 0.02 |
| L.DC | 13.3 ± 0.03 | 13.6 ± 0.02 | 0 | 0 |
| R.E | 9 ± 0.03 | 13.7 ± 0.02 | 53.8 ± 0.03 | 86.8 ± 0.06 |
| R.DC | 14.8 ± 0.06 | 18.3 ± 0.02 | 0 | 0 |
| S.E | 0.9 ± 0.03 | 0 | 0 | 40.2 ± 0.01 |
| S.DC | 7.4 ± 0.04 | 10.1 ± 3 | 0 | 0 |
| Kojic acid | 42.2 ± 0.2 | 83.3 ± 0.2 | 99 ± 0.1 | 100 ± 0.5 |
| Arbutin | 0 | 0 | 8.7 ± 0.8 | 32.6 ± 0.1 |
F.E - Fruits, ethanol extract; F.DC - Fruits, dichloromethane extract; L. E - Leaves, ethanol extract; F.DC - Leaves, dichloromethane extract; R. E - Root, ethanol extract;R. DC - Root, dichloromethane extract; S.E - Stem, ethanol extract; S.DC - Stem, dichloromethane extract Data are mean ± SD of three separate experiments