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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Expert Rev Anti Infect Ther. 2010 Apr;8(4):435–454. doi: 10.1586/eri.10.14

Figure 3. Factors critical for successful probiotic, prebiotic and synbiotic trials.

Figure 3

Consideration of interpersonal genetic and microbiome variations, standardized trials with defined outcomes and characterized strains coupled with high-resolution microbial phylogeny, microbiome functional profiles and host responses, are necessary to fully understand the potential impact of microbiome manipulation through probiotic, prebiotic or symbiotic supplementation.