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. Author manuscript; available in PMC: 2010 Jun 7.
Published in final edited form as: J Immunol. 2007 Sep 1;179(5):3144–3152. doi: 10.4049/jimmunol.179.5.3144

FIGURE 6.

FIGURE 6

Inhibition of HIV-1 transfer from epithelial cells to PBMC target cells by b12 mAbs. Cell-free HIV-1BaL or HIV-1IIIb preparations were incubated with IgG1 or IgA2 b12, and then applied to confluent monolayers of ME180 cells (left, A and B) or Caco-2 cells (right, C and D). Transfer was assessed by the addition of activated PBMCs and measuring p24 levels in culture supernatants by ELISA. The IC50 (micrograms per milliliter) is indicated in the inset table. Isotype-matched control Abs of irrelevant specificities showed no inhibition of HIV-1 transfer (data not shown).