Table 1.

Baseline sleep-architecture parameters and PLMS index in normal control subjects and patients with RLS

	Controls (n = 13)	RLS (n = 34)	P Value
TIB, min	503.2 ± 78.87	525.9 ± 67.36	NS
SPT, min	463.0 ± 58.40	488.6 ± 70.89	NS
TST, min	376.7 ± 57.02	390.0 ± 79.83	NS
Sleep latency, min
Overall	28.2 ± 30.10	25.4 ± 28.75	NS
REM	67.8 ± 37.85	113.8 ± 61.22	0.018
Stage shift, no/h	9.4 ± 2.17	11.8 ± 4.19	NS
Awakenings, no/h	4.6 ± 2.86	4.4 ± 2.57	NS
Sleep efficiency,%	76.1 ± 14.44	74.4 ± 13.18	NS
WASO, %	17.7 ± 14.68	20.1 ± 12.81	NS
Sleep stage, %
1	4.4 ± 3.82	5.8 ± 4.72	NS
2	50.5 ± 13.11	42.0 ± 10.31	NS
SWS	11.2 ± 9.25	15.8 ± 8.36	NS
REM	16.2 ± 6.87	16.3 ± 6.11	NS
PLMS index	9.2 ± 10.40	41.0 ± 28.41	0.00002a

Data are presented as mean ± SD. The Mann-Whitney test was used to determine the P values. The percentages of wakefulness after sleep onset (WASO) and sleep stages are referred to sleep period time (SPT).

RLS refers to restless legs syndrome; PLMS, periodic leg movements of sleep; TIB, time in bed; TST, total sleep time; REM, rapid eye movement; SWS, slow wave sleep

^aSignificant after Bonferroni correction.