Table 1.
General characteristics of 16 men with OSA and 16 healthy control subjects
| Patients with OSA (n = 16) | Healthy control subjects (n = 16) | P value | |
|---|---|---|---|
| Age, y | 50.9 ± 2.1 | 51.2 ± 1.7 | 0.4 |
| BMI, kg/m2 | 25.9 ± 0.5 | 25.0 ± 0.5 | 0.17 |
| PtcCO2, mm Hg | 38.5 ± 0.5 | 37.9 ± 0.9 | 0.7 |
| IOP, mm Hg | 13.9 ± 0.3 | 16.3 ± 0.7 | 0.01 |
| OPP, mm Hg | 53.7 ± 1.3 | 46.9 ± 1.0 | 0.001 |
| Sleep evaluation | |||
| AHI, no./h of sleep | 40.1 ± 3.9 | 4.91 ± 0.9 | < 0.001 |
| Mean nocturnal SaO2,% | 94.0 ± 0.5 | 93.7 ± 0.4 | 0.9 |
| Time spent at SaO2 < 90%, min | 25.8 ± 7.8 | 8.2 ± 6.9 | 0.001 |
| Cardiovascular phenotype | |||
| Systemic hypertensiona | 7 (43.7) | 3 (18.7) | 0.2 |
| Blood pressure, mm Hg | |||
| Systolic | 136.6 ± 3.8 | 129.2 ± 1.5 | 0.08 |
| Diastolic | 86.4 ± 3.1 | 83.3 ± 2.0 | 0.34 |
| Mean | 102.4 ± 6.7 | 95.7 ± 1.6 | 0.01 |
| Physiologic dipping | 5 (31.2) | 6(37.5) | 0.3 |
| Arterial stiffness, m/sec | 10.2 ± 0.6 | 9.2 ± 0.6 | 0.06 |
| Carotid IMT, μm | |||
| Right | 0.62 ± 0.02 | 0.57 ± 0.02 | 0.04 |
| Left | 0.64 ± 0.04 | 0.62 ± 0.03 | 0.9 |
| Carotid plaque | 3 (18.7) | 0 | 0.2 |
| LVEF, % | 66 ± 0.01 | 66 ± 0.019 | 0.9 |
| Dyslipidemia | 2 (11.1) | 2 (11.1) | 0.99 |
All data are expressed as mean ± SEM or number (%). OSA refers to obstructive sleep apnea; BMI, body mass index; PtcCO2; transcutaneous carbon-dioxide tension; IOP, intraocular pressure; OPP, ocular perfusion pressure; IMT, intima-media thickness; LVEF, left ventricular ejection fraction;
a
As determined by ambulatory blood pressure monitoring.