Table A4.
Comparing the Genotype Frequency Distribution Difference Among the Three Study Populations
| Gene and SNP | Patients |
χ2 Test P | ||
|---|---|---|---|---|
| MDACC (N = 590) | UCSF (N = 352) | Sweden (N = 191) | ||
| LIG4 rs7325927 | ||||
| CC | 309 | 182 | 105 | MDACC–UCSF, P = .002 |
| TC | 217 | 153 | 65 | MDACC–Sweden, P = .008 |
| TT | 64 | 17 | 6 | UCSF–Sweden, P = .208 |
| CCDC26 rs10464870 | ||||
| TT | 350 | 225 | 105 | MDACC–UCSF, P = .356 |
| TC | 210 | 111 | 55 | MDACC–Sweden, P = .204 |
| CC | 31 | 16 | 15 | UCSF–Sweden, P = .171 |
| CCDC26 rs891835 | ||||
| TT | 335 | 210 | 103 | MDACC–UCSF, P = .646 |
| TG | 224 | 123 | 59 | MDACC–Sweden, P = .155 |
| GG | 32 | 19 | 16 | UCSF–Sweden, P = .287 |
| RTEL1 rs2297440 | ||||
| CC | 391 | 251 | 114 | MDACC–UCSF, P = .056 |
| TC | 179 | 95 | 57 | MDACC–Sweden, P = .885 |
| TT | 19 | 4 | 6 | UCSF–Sweden, P = .074 |
Abbreviations: MDACC, M. D. Anderson Cancer Center; UCSF, University of California San Francisco.