Table 3.
Treatment and Toxicity | Grade |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
2 |
3 |
4 |
5 |
||||||
No. | % | No. | % | No. | % | No. | % | No. | % | |
Chemotherapy and acute radiotherapy toxicity (n = 53) | ||||||||||
Allergy/immunology | 1 | 0 | 1 | 1 | 0 | |||||
Auditory/hearing | 1 | 2 | 0 | 0 | 0 | |||||
Blood/bone marrow | 7 | 10 | 24 | 3 | 0 | |||||
Cardiovascular (arrhythmia) | 0 | 3 | 4 | 0 | 0 | |||||
Cardiovascular (general) | 2 | 2 | 7 | 0 | 0 | |||||
Coagulation | 2 | 0 | 2 | 0 | 0 | |||||
Constitutional symptoms | 16 | 21 | 3 | 0 | 0 | |||||
Dermatology/skin | 20 | 9 | 1 | 0 | 0 | |||||
Gastrointestinal | 9 | 26 | 12 | 0 | 0 | |||||
Hemorrhage | 5 | 0 | 1 | 0 | 1 | |||||
Hepatic | 9 | 4 | 0 | 0 | 0 | |||||
Infection febrile neutropenia | 0 | 1 | 6 | 0 | 0 | |||||
Metabolic/laboratory | 8 | 4 | 5 | 0 | 0 | |||||
Musculoskeletal | 1 | 1 | 0 | 0 | 0 | |||||
Neurology | 12 | 7 | 5 | 0 | 0 | |||||
Pain | 10 | 12 | 6 | 0 | 0 | |||||
Pulmonary | 10 | 11 | 8 | 1 | 1 | |||||
Renal/genitourinary | 5 | 2 | 2 | 0 | 0 | |||||
Sexual/reproductive function | 1 | 0 | 0 | 0 | 0 | |||||
Worst nonhematologic | 4 | 8 | 16 | 30 | 28 | 53 | 2 | 4 | 2 | 4 |
Worst hematologic | 1 | 2 | 8 | 15 | 37 | 70 | 5 | 9 | 2 | 4 |
Late radiotherapy toxicity (n = 50) | ||||||||||
Bone | 1 | 0 | 0 | 0 | 0 | |||||
Esophagus | 6 | 1 | 4 | 0 | 0 | |||||
Heart | 0 | 3 | 1 | 0 | 0 | |||||
Lung | 11 | 9 | 6 | 1 | 1 | |||||
Other | 4 | 4 | 0 | 0 | 0 | |||||
Skin (within the irradiated field) | 5 | 0 | 0 | 0 | 0 | |||||
Spinal cord | 1 | 0 | 0 | 0 | 0 | |||||
Subcutaneous tissue | 2 | 0 | 0 | 0 | 0 | |||||
Worst overall | 13 | 26 | 10 | 20 | 9 | 18 | 1 | 2 | 1 | 2 |