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. 2010 Apr 5;28(14):2475–2480. doi: 10.1200/JCO.2009.27.1205

Table 3.

Toxicity for Patients With Grades 1-5 Lung Toxicity

Treatment and Toxicity Grade
1
2
3
4
5
No. % No. % No. % No. % No. %
Chemotherapy and acute radiotherapy toxicity (n = 53)
    Allergy/immunology 1 0 1 1 0
    Auditory/hearing 1 2 0 0 0
    Blood/bone marrow 7 10 24 3 0
    Cardiovascular (arrhythmia) 0 3 4 0 0
    Cardiovascular (general) 2 2 7 0 0
    Coagulation 2 0 2 0 0
    Constitutional symptoms 16 21 3 0 0
    Dermatology/skin 20 9 1 0 0
    Gastrointestinal 9 26 12 0 0
    Hemorrhage 5 0 1 0 1
    Hepatic 9 4 0 0 0
    Infection febrile neutropenia 0 1 6 0 0
    Metabolic/laboratory 8 4 5 0 0
    Musculoskeletal 1 1 0 0 0
    Neurology 12 7 5 0 0
    Pain 10 12 6 0 0
    Pulmonary 10 11 8 1 1
    Renal/genitourinary 5 2 2 0 0
    Sexual/reproductive function 1 0 0 0 0
    Worst nonhematologic 4 8 16 30 28 53 2 4 2 4
    Worst hematologic 1 2 8 15 37 70 5 9 2 4
Late radiotherapy toxicity (n = 50)
    Bone 1 0 0 0 0
    Esophagus 6 1 4 0 0
    Heart 0 3 1 0 0
    Lung 11 9 6 1 1
    Other 4 4 0 0 0
    Skin (within the irradiated field) 5 0 0 0 0
    Spinal cord 1 0 0 0 0
    Subcutaneous tissue 2 0 0 0 0
    Worst overall 13 26 10 20 9 18 1 2 1 2