TABLE 2.

Interstrand residue pairing preferences from two-stranded β-sheets in the data set

Values are the z scores measuring the differences between actual and expected frequency counts as described under “Materials and Methods.” Values larger than 2.5 are shown in bold and double underlined.

	Ala	Val	Leu	Ile	Phe	Tyr	Met	Cys	Trp	His	Glu	Gln	Lys	Arg	Ser	Thr	Asp	Asn	Gly	Pro
Ala	0.81
Val	1.14	1.49
Leu	1.38	1.31	1.37
Ile	0.73	1.22	1.18	1.86
Phe	0.59	1.02	1.02	1.28	1.33
Tyr	1.37	1.12	1.00	0.93	1.18	0.88
Met	2.01	1.09	0.73	0.81	0.65	1.52	0.99
Cys	1.11	0.31	1.44	1.45	0.71	0.77	0.82	13.4
Trp	1.78	0.75	1.16	0.75	1.23	1.86	1.12	3.24	1.28
His	1.93	0.82	1.57	0.79	1.05	1.13	0.00	0.00	0.00	2.30
Glu	0.19	0.77	1.11	0.90	0.60	0.84	1.05	0.52	1.19	0.45	0.53
Gln	0.63	0.84	0.92	0.83	0.92	1.32	0.70	0.00	0.79	1.13	1.33	0.99
Lys	0.68	0.87	0.68	0.93	0.66	1.19	0.81	0.83	1.49	0.87	2.57	1.14	0.49
Arg	0.86	0.69	0.73	1.16	1.48	1.59	1.35	0.00	0.89	0.73	2.34	0.40	0.60	0.82
Ser	0.77	0.68	0.39	0.70	1.32	0.56	0.79	2.39	1.05	0.85	0.89	1.86	1.45	1.32	1.40
Thr	1.09	0.97	0.35	0.76	0.93	0.77	0.71	0.23	0.32	1.38	0.75	1.00	0.78	0.64	1.21	2.65
Asp	0.86	0.61	0.42	0.19	0.56	0.15	0.95	0.00	0.72	2.74	1.01	1.35	2.78	1.73	1.27	0.91	0.61
Asn	0.75	0.72	0.86	0.49	1.00	0.20	0.42	0.69	0.47	0.90	1.06	2.20	1.36	1.04	0.88	1.37	1.20	1.75
Gly	1.44	1.11	0.94	0.90	0.86	1.00	1.21	1.50	1.03	0.33	0.71	0.64	0.25	0.28	0.81	1.31	2.14	1.02	0.74
Pro	1.04	0.76	1.36	0.59	1.59	1.25	1.65	1.09	1.12	0.00	0.84	0.47	0.27	1.72	1.32	0.99	0.64	1.66	1.21	0.88