TABLE 3.
Crystallographic contacts in NS2B18NS3 conformation I and II
| No. of contacts between symmetry-related molecules, excluding water molecules | Conformation I | Conformation II |
|---|---|---|
| NS2B18NS3, 647 residues | 46 (0.071)a | 62 (0.096) |
| Protease domain, 197 residues | 5 (0.025) | 12 (0.061) |
| Helicase domain, 438 residuesb | 41 (0.094) | 50 (0.114) |
a The numbers in parentheses refer to average number of contacts per residue.
b In total, 22 pairs of contact are exactly in common between neighboring helicase domains in the two structures and none from the protease domain.