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. 2010 Apr 13;285(24):18888–18898. doi: 10.1074/jbc.M110.110924

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — Alignment of human NAT8 and NAT8B with related sequences and with NAT8L (aspartate N-acetyltransferase). The following sequences are shown: Homo sapiens NAT8, NAT8B, and NAT8L (HsapiensNAT8, gi:47115157; HsapiensNAT8B, gi:117168283; HsapiensNAT8L, gi:259016335); Canis familiaris (CfamiliarisCML2, gi:7398098); Mus musculus (MmusculusCML5, gi:19353130); Gallus gallus (GgallusNAT8B, gi:118110777); and D. rerio NAT8L (DrerioNAT8L, gi:139947555). The human NAT8B coding sequence includes a stop codon (X) at codon 16. G23R and Q168X (underlined in Hsapiens NAT8B) are two frequent alleles. E104K and S143F (underlined in HsapiensNAT8) are two common SNPs shown for the human NAT8 coding sequence. Residues strictly conserved among all sequences shown are in boldface. Residues conserved among the NAT8-related sequences are in blue. Residues conserved among the two NAT8L sequences are in red.