Skip to main content
. Author manuscript; available in PMC: 2010 Jun 8.
Published in final edited form as: J Immunol. 2009 Dec 15;183(12):7787–7798. doi: 10.4049/jimmunol.0902318

FIGURE 6.

FIGURE 6

Treatment with GMSCs ameliorates DSS-induced experimental colitis in C57BL/6 mice. Colitis was induced by oral administration of 3% DSS in drinking water for 7 days. Two × 106 of GMSCs or BMSCs in 200 μl of PBS were i.p. injected into mice 1 day after initiation of DSS treatment. Mice without any treatment (naive mice) or mice that received 200 μl of PBS served as controls. At day 10, mice were sacrificed. A and B, Clinical progression of the disease was monitored by body weight changes (A) and colitis score evaluation (B), whereas in A, *, p < 0.05 and **, p < 0.01 compared with DSS alone. C, Colonic MPO activity assays. D and E, Histopathological analysis of colitis. IF, Inflammation. Scale bar, 200 μm. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ns, no significant difference (mean ± SD). The results are representative of at least three independent experiments.