. 2010 Apr 27;25(7):731–740. doi: 10.1007/s11606-010-1354-5

Table 6.

Effect of Selected Drugs on Calcineurin Inhibitor Concentrations

Concentrations increased by¹⁸⁵	Concentrations decreased by¹⁵⁵^,¹⁸⁸
Macrolide antibiotics	Anticonvulsants (phenobarbital, phenytoin,carbamazepine)
Calcium channel blockers	Rifampicin
(Diltiazem, verapamil)
Triazole antifungals	Dexamethasone
Protease inhibitors	St John’s Wort (used for depression)
Amiodarone	Marijuana
Metoclopramide	Orlistat
Grapefruit juice	Octreotide
Ciprofloxacin
Selective serotonin reuptake inhibitors (SSRIs)