Table 2.
Estimated amounts of Gd (µg Gd/g tissue) in selected organs/tissues from rats injected with Omniscan with trace amounts of 14C-labelled GdDTPA-BMA. Data are given as mean ± SD (n = 3)
| Tissues | Time after injection | ||||
|---|---|---|---|---|---|
| 1 h | 4 h | 24 h | 3 days | 7 days | |
| Kidney | 72.6 ± 13.2 | 36.5 ± 7.58 | 30.0 ± 5.19 | 23.6 ± 1.04 | 12.7 ± 0.96 |
| Liver | 7.40 ± 2.11 | 2.44 ± 0.98 | 1.56 ± 0.21 | 0.88 ± 0.13 | 0.53 ± 0.15 |
| Lung | 10.4 ± 2.46 | 1.75 ± 1.01 | 0.88 ± 0.02 | 0.71 ± 0.09 | 0.48 ± 0.02 |
| Muscle | 3.20 ± 0.52 | 0.55 ± 0.11 | 0.35 ± 0.05 | 0.21 ± 0.01 | 0.16a |
| Skin | 5.36 ± 1.28 | 1.22 ± 0.28 | 0.76 ± 0.11 | 0.52 ± 0.12 | 0.39 ± 0.16 |
| Bone | 6.05 ± 1.62 | 3.47 ± 0.43 | 3.55 ± 0.19 | 4.45 ± 0.49 | 4.92 ± 0.11 |
aOnly one sample above limit of quantitation