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. Author manuscript; available in PMC: 2010 Jun 8.
Published in final edited form as: Biochemistry. 2010 May 18;49(19):4116–4125. doi: 10.1021/bi100102s

Figure 5.

Figure 5

Progress curves for wt RB69pol and the Y567A mutant for insertion of d(3DA)MP opposite T and dTMP opposite 3DA. A. Shown is the purine numbering scheme (left) and 3-deazaadenine (3DA) (right). B. Rate of DNA product formation for dTMP insertion opposite 3DA by wt (▲), dTMP opposite A by wt (▼), and dTMP opposite 3DA by the Y567A mutant (■). C. Rate of DNA product formation for d(3DA)TP insertion opposite T by wt (■), dATP opposite T by wt (●), and dTMP opposite 3DA by the Y567A mutant ▲.