Table 2.
Characteristics of children new to asthma controller therapy, stratified by full cohort and survey responder cohort
| Characteristic | Full cohort (n = 10,004) | Survey responders (n = 635) | p value |
|---|---|---|---|
| Mean age (SD), yr | 8.0 (3.8) | 8.1 (3.8) | 0.35 |
| Age 0-2 yr, n (%) | 806 (8.1%) | 51 (8.0%) | |
| Age 3-5 yr, n (%) | 2155 (21.5%) | 143 (22.5%) | |
| Age 6-8 yr, n (%) | 2307 (23.1%) | 126 (19.8%) | |
| Age 9-11 yr, n (%) | 2402 (24.0%) | 165 (26.0%) | |
| Age 12-14 yr, n (%) | 2334 (23.3%) | 150 (23.6%) | |
| Male sex, n (%) | 5942 (59.4%) | 365 (57.5%) | 0.29 |
| Smoking status | 0.22 | ||
| Non smoker | 5651 (56.5%) | 366 (57.6%) | |
| Smoker | 532 (5.3%) | 31 (4.9%) | |
| Ex smoker | 77 (0.8%) | 6 (0.9%) | |
| Passive smoker | 152 (1.5%) | 3 (0.5%) | |
| Unknown smoking status | 3592 (35.9%) | 229 (36.1%) | |
| BMI, n | 5816 | 393 | |
| Mean BMI (SD) | 17.3 (5.3) | 17.1 (5.0) | 0.32 |
| Median BMI (range) | 16.6 (5.0-49.6) | 16.7 (5.2-47.7) | 0.75 |
| Asthma duration: mean (SD), yr | 4.3 (3.6) | 4.4 (3.6) | 0.56 |
| Median (range), yr | 3.7 (0.0-15.0) | 3.9 (0.0-14.0) | 0.62 |
| Asthma controller therapy prescription at index date, n (%) | 0.437 | ||
| ICS monotherapy | 9059 (90.6%) | 575 (90.6%) | |
| LABA in fixed dose combination | 574 (5.7%) | 43 (6.8%) | |
| ICS + LABA | 124 (1.2%) | 4 (0.6%) | |
| LTRA monotherapy | 91 (0.9%) | 6 (0.9%) | |
| ICS + LTRA | 55 (0.6%) | 1 (0.2%) | |
| Other | 101 (1.0%) | 6 (0.9%) | |
BMI = body mass index; ICS = inhaled corticosteroids; LABA = long-acting β2-agonists (in fixed dose combination is with ICS); LTRA = leukotriene receptor antagonists.