Table 3. Patient Characteristics.
| Site | Patient | Dog's Sex | Age | Breed | Primary Disease Site | Stage of Disease | Cohort |
| CSU | 0201 | Spayed female | 8.6 | Rottweiler | Humerus | I | 0.01 mg/kg IM daily |
| OSU | 0601 | Spayed female | 5.1 | Mixed Breed | Tibia | II | 0.01 mg/kg IM daily |
| UW | 0501 | Castrated male | 9.3 | Weimaraner | Radius | 0.01 mg/kg IM daily | |
| OSU | 0602 | Castrated male | 5.7 | Great Pyrenees | Tibia | II | 0.02 mg/kg IM daily |
| OSU | 0603 | Spayed female | 9.1 | Weimaraner | Humerus | II | 0.02 mg/kg IM daily |
| OSU | 0604 | Castrated male | 5.9 | Saint Bernard | Radius | II | 0.02 mg/kg IM daily |
| UIL | 0701 | Castrated male | 8.8 | Irish Setter | Humerus | IIB | 0.02 mg/kg IM daily |
| OSU | 0605 | Spayed female | 11.9 | Mixed Breed | Humerus | II | 0.04 mg/kg IM daily |
| UIL | 0702 | Spayed female | 8 | Boxer | Tibia | IIB | 0.04 mg/kg IM daily |
| UIL | 0703 | Spayed female | 8.2 | Mixed Breed | Radius | IIB | 0.04 mg/kg IM daily |
| CSU | 0202 | Spayed female | 3.7 | Great Pyrenees | Tibia | II | 0.06 mg/kg IM daily |
| CSU | 0203 | Spayed female | 7.1 | Mixed Breed | Radius | II | 0.06 mg/kg IM daily |
| CSU | 0204 | Spayed female | 4.6 | Great Dane | Radius | II | 0.06 mg/kg IM daily |
| CSU | 0205 | Spayed female | 8.7 | Labrador Retriever | Humerus | II | 0.06 mg/kg IM daily |
| OSU | 0606 | Spayed female | 10.2 | Rottweiler | Tibia | 0.06 mg/kg IM daily | |
| UIL | 0704 | Castrated male | 6 | Irish Wolfhound | Tibia | IIB | 0.06 mg/kg IM daily |
| UIL | 0705 | Castrated male | 3.9 | Beagle | Humerus | IIA | 0.06 mg/kg IM daily |
| CSU | 0207 | Castrated male | 5.8 | Rottweiler | Humerus | I | 0.08 mg/kg IM daily |
| CSU | 0208 | Castrated male | 11.7 | Labrador Retriever | Radius | I | 0.08 mg/kg IM daily |
| UIL | 0706 | Spayed female | 6.1 | Mixed Breed | Radius | IIB | 0.08 mg/kg IM daily |
| UIL | 0707 | Spayed female | 10.4 | Greyhound | Femur | IIB | 0.08 mg/kg IM daily |
| UIL | 0708 | Spayed female | 7.8 | Rottweiler | Femur | IIB | 0.08 mg/kg IM daily |
Site of enrollment: CSU = Colorado State University, UIL = University of Illinois, OSU = Ohio State University, UW = University of Wisconsin; WHO staging for canine osteosarcoma: Stage I = low grade primary tumor, A = intracompartmental tumor, B = extracompartmental tumor, Stage II = high grade primary tumor/no metastatic disease (N0 and M0), A = intracompartmental tumor (in marrow), B = extracompartmental tumor.
Stage III = low or high grade primary tumor with metastatic disease (N1 or M1), A = intracompartmental tumor, B = extracompartmental tumor.