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. 2010 Jun 15;182(9):895–901. doi: 10.1503/cmaj.091876

Table 4.

Information reported about the use of life-ending drugs in physician-assisted deaths*

Information Physician-assisted death, weighted %* p value§
With patient’s explicit requestn = 142 Without patient’s explicit request n = 66
Number of drugs used 0.038
 1 33.2 51.4
 ≥ 2 66.8 48.6
Type of drugs used < 0.001
 Muscle relaxant 0.5
 Muscle relaxant and barbiturate 29.0 0.9
 Muscle relaxant and drug other than barbiturate 6.4
 Barbiturate 9.8
 Barbiturate and drug other than muscle relaxant 9.5 1.0
 Opioid 21.9 48.7
 Opioid and drug other than muscle relaxant and barbiturate 21.9 46.6
 Benzodiazepine 1.0 2.7
Person who administered drugs 0.018
 Physician 69.6 47.2
 Physician and nurse 8.1 17.4
 Nurse 18.9 33.8
 Patient 1.0
 Physician and patient 2.4
 Nurse and someone else** 1.6
Physician present during administration†† 86.7 79.9 0.35
*

Percentages are weighted to correct for the disproportionate stratification of deaths and for differences in the distribution of patient characteristics between study sample and all deaths. Percentages may not total 100 because of rounding.

Euthanasia and assisted suicide. Two cases missing for number of drugs used and for drugs used.

One case missing for number of drugs used and for drugs used.

§

Calculated using Fisher exact test, for comparison between physician-assisted death with and without explicit request from the patient.

**

Relative of the patient.

††

Includes cases in which physician administered drugs or was present during administration of drugs by someone else.