FIG. 7.
Lipoic acid altered gene expression in differentiated C2C12 cells. Lipoic acid at 1000 μM for 16 h induced gene expressions in differentiated C2C12 cells. Gene expression was measured by real-time qRT-PCR and expressed in terms of mRNA levels relative to 18S rRNA. Lipoic acid stimulation had significantly elevated mRNA levels of PGC-1α and GLUT-4. Each treatment was repeated at least three times. Data are presented as mean ± SEM. **P < 0.01.