Table 1.
Rates and rates relative to vehicle (RRV) of EGFP-hAR transport for 4 doses of TEST, ANE, DHT, EPI, MET, NAN, OXA, and FLU and for VEH. Rate is min−1.
1 nM | 10 nM | 50 nM | 100 nM | |||||
---|---|---|---|---|---|---|---|---|
rate | RRV | rate | RRV | rate | RRV | rate | RRV | |
TEST | 0.0069 | 2.13 | 0.0134* | 4.12 | 0.0525* | 16.11 | 0.0301* | 9.24 |
ANE | 0.0029 | 0.90 | 0.0058 | 1.78 | 0.0157* | 4.83 | 0.0112* | 3.45 |
DHT | 0.0012 | 0.38 | 0.0179* | 5.51 | 0.0100* | 3.06 | 0.0200* | 6.15 |
EPI | 0.0046 | 1.42 | 0.0096 | 2.96 | 0.0118* | 3.63 | 0.0130* | 4.00 |
MET | 0.0114 | 3.50 | 0.0157* | 4.81 | 0.0339* | 10.41 | 0.0212* | 6.51 |
NAN | 0.0130* | 4.00 | 0.0261* | 8.03 | 0.0220* | 6.76 | 0.0261* | 8.01 |
OXA | 0.0047 | 1.43 | 0.0213* | 6.53 | 0.0276* | 8.48 | 0.0196* | 6.02 |
FLU | 0.0059 | 1.80 | 0.0035 | 1.06 | 0.0153* | 4.71 | 0.0033 | 1.02 |
VEH | 0.0033 | 1.00 |
Rates significantly different from vehicle, p < 0.05.