Table 3.
Mean fasting insulin, 2H-OGTT insulin and HOMA-1 by BMI and central adiposity (%TF and WC) groups in 3280 Chinese women aged 20–60 years with NGT.
| Adiposity | N | Fasting ln(insulin) | 2H-OGTT ln(insulin) | HOMA-1 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± SD | β(se) | p | Mean ± SD | β(se) | p | Mean ± SD | β(se) | p | |||
| BMI | %TF a | ||||||||||
| <23 | Low | 1882 | 1.6 ± 0.8 | Ref | -- | 2.8 ± 0.9 | Ref | -- | 1.3 ± 1.2 | Ref | -- |
| High | 373 | 1.7 ± 0.8 | 0.13(0.05) | 0.0045 | 2.9 ± 0.9 | 0.12(0.05) | 0.0308 | 1.4 ± 1.0 | 0.13(0.06) | 0.0353 | |
| ≥23 | Low | 578 | 1.6 ± 0.7 | Ref | -- | 2.8 ± 0.9 | Ref | -- | 1.3 ± 1.2 | Ref | -- |
| High | 447 | 1.8 ± 0.8 | 0.14(0.05) | 0.0058 | 3.0 ± 0.9 | 0.17(0.06) | 0.0059 | 1.6 ± 1.6 | 0.24(0.09) | 0.0109 | |
| BMI | WC | ||||||||||
| <23 | <80 | 2195 | 1.6 ± 0.8 | Ref | -- | 2.8 ± 0.9 | Ref | -- | 1.3 ± 1.2 | Ref | -- |
| ≥80 | 60 | 1.7 ± 0.7 | 0.19(0.09) | 0.0418 | 2.9 ± 0.8 | 0.24(0.1) | 0.0235 | 1.4 ± 1.0 | 0.14(0.13) | 0.2639 | |
| ≥23 | <80 | 590 | 1.7 ± 0.8 | Ref | -- | 2.9 ± 1.0 | Ref | -- | 1.4 ± 1.3 | Ref | -- |
| ≥80 | 435 | 1.7 ± 0.7 | 0.05(0.05) | 0.3429 | 2.9 ± 0.9 | 0.04(0.06) | 0.5739 | 1.4 ± 1.5 | 0.07(0.09) | 0.4666 | |
*
Adjusted for age, age2, previous and current alcohol drinking, education, occupation and correlations among twin pairs.
a
High %TF defined as highest quartile for entire study population.