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. Author manuscript; available in PMC: 2010 Jun 9.
Published in final edited form as: Cell. 2009 Apr 23;137(3):522–535. doi: 10.1016/j.cell.2009.03.040

Figure 6. Piwi Localization and Loading in Germline Cells Requires Armitage.

Figure 6

(A) Piwi protein localization in wild-type and armi1/72.1 mutant ovaries.

(B) Densities of uniquely mapping, Piwi-bound piRNAs over the 42AB and flamenco clusters from the wild-type (Oregon R, black) and armi mutants (yellow).

(C) Annotation of repeat derived, Piwi-bound piRNAs from wild-type and armi mutant ovaries.

(D) Log2 fold changes of cluster-derived piRNAs in an armi mutant total RNA library compared to heterozygote.

(E) Log2 fold changes of piRNAs mapping antisense to indicated transposons in armi and spn-E mutants compared to respective heterozygotes are shown in heat map form. Corresponding ping-pong signal heat maps are shown (right).

(F) piRNA densities over indicated transposons in heterozygote (black) and armi mutant (yellow) libraries.

(G) F element ping-pong profiles in armi heterozygote (black), armi mutant (yellow), and aub mutant (blue) libraries.