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Implications for management from studies of endothelial function in diabetes
| No benefit from traditional antioxidants (vitamin E and vitamin C) |
| ACE inhibitors and ARB’s preferred |
| Statin therapy beneficial |
| Intensive glucose control/Insulin sensitizers should be beneficial |
| Merit further clinical study: |
| PKCβ inhibitors |
| NFκB inhibitors |
| Mitochondrial directed therapy—inhibit fission, augment fusion and autophagy |
| Practical methods to monitor endothelial function |
