Table 1.
Numbers of genes in various functional classes included in this study
| GO categorya | Molecular function | No. of genes |
|---|---|---|
| GO:0004871 | Signal transducer activity | 86 |
| GO:0005102 | Receptor binding | 44 |
| GO:0001664 | G-protein-coupled receptor binding | 41 |
| GO:0003676 | Nucleic acid binding | 21 |
| GO:0000166 | Nucleotide binding | 19 |
| GO:0001584 | Rhodopsin-like receptor activity | 16 |
| GO:0005488 | Binding | 12 |
| GO:0003824 | Catalytic activity | 7 |
| GO:0004857 | Enzyme inhibitor activity | 6 |
| GO:0003823 | Antigen binding | 3 |
| GO:0001871 | Pattern binding | 3 |
| GO:0001530 | Lipopolysaccharide binding | 2 |
| GO:0008009 | Chemokine activity | 1 |
| GO:0001948 | Glycoprotein binding | 1 |
| GO:0015457 | Auxiliary transport protein activity | 1 |
| GO:0032393 | MHC class I receptor activity | 1 |
| GO:0003774 | Motor activity | 1 |
| GO:0032395 | MHC class II receptor activity | 1 |
| GO:0001532 | Interleukin-21 receptor activity | 1 |
| GO:0005125 | Cytokine activity | 1 |
| GO:0000287 | Magnesium ion binding | 1 |
| GO:0005048 | Signal sequence binding | 1 |
| GO:0005515 | Protein binding | 1 |
| GO:0001540 | Beta-amyloid binding | 1 |
| GO:0005215 | Transporter activity | 1 |
| GO:0003712 | Transcription cofactor activity | 1 |
| Miscellaneous (GO category unavailable; information obtained from UNIPROTb database) | Mediation of inflammation and angiogenesis | 1 |
| Peptide binding | 1 | |
| Antimicrobial activity | 3 | |
| T-cell activation | 1 | |
| Defense response with MHC | 1 | |
| Regulation of inflammatory responses | 1 | |
| Putative immune function (Gene: HCG9; lies within MHC class I region) | 1 | |
| Total | 283 | |
aGO (Gene Ontology) category was obtained from gene2go file of NCBI Entrez Gene database (ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/)