Skip to main content
. Author manuscript; available in PMC: 2010 Jul 6.
Published in final edited form as: Cancer Biol Ther. 2009 Jul 6;8(13):1212–1213. doi: 10.4161/cbt.8.13.8630

Figure 4. Cox-2 and RARβ2 mRNA levels in control (not treated with 4-NQO) and 4-NQO treated mouse tongues.

Figure 4

K14/FLAG-hLRAT TG positive and negative mice were treated with propylene glycol (vehicle) or 4-NQO (100 μg/ml) in drinking water (see “Materials and Methods”) for 10 weeks and then maintained for another 15 weeks. Total RNA was extracted from mouse tongues and specific mRNA levels were measured by real time RT-PCR. A, Cox-2 mRNA. B, RARβ2 mRNA. The data were analyzed by using a Wilcoxon rank sum test. Differences of mRNA levels between TG+ and TG- mouse tongues with a p value of < 0.05 (marked with an asterisk) were considered to be statistically significant.