TABLE 6.
Multiple linear regression analyses demonstrating relationships of high density lipoprotein cholesterol and apolipoprotein A-I with estimated glomerular filtration rate (e-GFR), creatinine clearance, clinical variables [waist circumference, insulin resistance (HOMAir)], triglycerides and urinary albumin excretion in 2,484 individuals. Analyses with creatinine clearance (in ml/min/1.73 m2); model 1 without and model 2 with urinary albumin excretion.
Model 1 |
Model 2 |
|||||||
---|---|---|---|---|---|---|---|---|
HDL-C |
ApoA-I |
HDL-C |
ApoA-I |
|||||
β | P | β | P | β | P | β | P | |
Creatinine clearance | −0.048 | 0.004 | −0.050 | 0.011 | −0.048 | 0.012 | −0.043 | 0.033 |
Waist | — | <0.001 | −0.163 | <0.001 | −0.207 | <0.001 | −0.160 | <0.001 |
Ln HOMAir | −0.064 | 0.001 | −0.065 | 0.005 | −0.063 | 0.001 | −0.064 | 0.005 |
Ln Trig | −0.335 | <0.001 | −0.033 | 0.121 | −0.334 | <0.001 | −0.033 | 0.128 |
Ln UAE | −0.018 | 0.296 | −0.026 | 0.180 |
All models are adjusted for age and sex. Apo, apolipoprotein; HDL-C, high-density lipoprotein cholesterol; HOMAir, homeostasis model assessment estimated insulin resistance; Ln, logarithmically transformed values; Trig, triglycerides; UAE, urinary albumin excretion; β, standardized regression coefficient.