TABLE 3.
The effect of PON1 genotype on the serum paraoxonase, diazoxonase and arylesterase activity
| Genotype | N | Paraoxonaseb | Diazoxonaseb | N | Arylesteraseb | ||||
|---|---|---|---|---|---|---|---|---|---|
| PON1 Q/R | Q/Q | 237 | 343 ± 14a | P < 0.001 | 10093 ± 198 | P < 0.001 | 94 | 8234 ± 174 | P < 0.002 |
| Q/R | 161 | 579 ± 21 | 8024 ± 207 | 68 | 7676 ± 240 | ||||
| R/R | 21 | 946 ± 56 | 5686 ± 392 | 11 | 6152 ± 689 | ||||
| PON1 M/L | L/L | 155 | 593 ± 24 | P < 0.001 | 9285 ± 270 | ns | 52 | 7734 ± 274 | ns |
| M/L | 207 | 429 ± 18 | 8812 ± 212 | 83 | 7737 ± 203 | ||||
| M/M | 63 | 223 ± 14 | 8912 ± 299 | 28 | 8017 ± 294 |
a
Mean ± SE, ns: not statistically significant.
b
Enzymatic activities are expressed as Units/L.