TABLE 5.
Correlation of the PON1 aryslesterase serum activity with parameters derived from laboratory measurements within the QQ and QR genotypic subset
| Arylesterase |
|||
|---|---|---|---|
| QR | |||
| Parameters | r-Pearsona (p) N | ||
| Body measurements | |||
| Waist circumference | −0.009 (0.936) 89 | 0.116 (0.359) 63 | |
| Body mass index | 0.032 (0.766) 89 | 0.133 (0.291) 63 | |
| Blood pressure | |||
| Systolic blood pressure | 0.032 (0.775) 82 | 0.099 (0.44) 60 | |
| Diastolic blood pressure | 0.007 (0.947) 82 | −0.131 (0.311) 60 | |
| Glucose and biochemical indexes | |||
| Glucose | 0.026 (0.812) 86 | 0.062 (0.618) 64 | |
| Total cholesterol | 0.114 (0.187) 90 | 0.307 (0.013) 63* | |
| Triglycerides | −0.006 (0.987) 88 | 0.240 (0.052) 64 | |
| HDL-C | 0.086 (0.413) 90 | 0.173 (0.164) 64 | |
| LDL-C | 0.108 (0.313) 87 | 0.252 (0.043) 63* | |
| Total cholesterol: HDL-C ratio | 0.049 (0.646) 90 | 0.120 (0.341) 63 | |
| Lipoprotein A | −0.096 (0.386) 82 | 0.060 (0.659) 55 | |
| Apo lipoprotein A1 | 0.086 (0.436) 82 | 0.067 (0.619) 55 | |
| Apo lipoprotein B | −0.051 (0.658) 77 | 0.313 (0.024) 50* | |
| Folate acid | 0.198 (0.214) 39 | 0.100 (0.606) 27 | |
| Serum vitamin B12 | −0.290 (0.070) 38 | 0.185 (0.336) 27 | |
| Serum iron | −0.012 (0.912) 84 | −0.017 (0.907) 49 | |
| Homocysteine | 0.239 (0.137) 38 | −0.230 (0.230) 27 | |
| Adipose tissue | |||
| Saturated fatty acids | 0.119 (0.298) 76 | −0.062 (0.625) 62 | |
| Mono-unsaturated fatty acids | −0.131 (0.253) 76 | 0.115 (0.365) 62 | |
| Poly-unsaturated fatty acids | 0.100 (0.386) 76 | −0.130 (0.306) 62 | |
| Trans fatty acids | −0.037 (0.749) 76 | −0.026 (0.836) 62 | |
| n3 | −0.153 (0.182) 76 | −0.004 (0.975) 62 | |
| n6 | 0.117 (0.307) 76 | −0.132 (0.297) 62 | |
| 18:2n6 (LA) | 0.131 (0.254) 76 | −0.146 (0.249) 62 | |
| 18:3n3 (LNA) | −0.018 (0.879) 76 | −0.052 (0.682) 62 | |
| 20:3n6 (dihomo-γ-linolenic) | −0.029 (0.501) 76 | 0.115 (0.365) 62 | |
| 20:4n6 (arachidonic) | −0.068 (0.557) 76 | 0.068 (0.593) 62 | |
| 20:5n3 (EPA) | −0.246 (0.030) 76* | −0.010 (0.935) 62 | |
| 22:6n3 (DHA) | −0.197 (0.084) 76 | 0.069 (0.588) 62 | |
a
Partial correlation coefficient. Controlling for age and gender. * P < 0.05, The RR subset was not evaluated due to size restrictions of the employed statistics.