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. 2010 May 12;65(7):1477–1485. doi: 10.1093/jac/dkq140

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© The Author 2010. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Treatment associations of NNRTI-selected mutations. This figure shows the associations of 52 NNRTI-selected mutations on treatment with efavirenz (EFV) or nevirapine (NVP), based on a Pearson's χ² analysis of the frequency of the mutation among sequences from individuals treated with EFV or NVP but no other NNRTI. (a) The 16 mutations preferentially selected (P < 0.05) by efavirenz; (b) the 12 mutations preferentially selected by nevirapine; (c) the remaining 24 mutations, which were not significantly associated with either drug.