Table 1.
Clinical characteristics of COPD patients and controls with airway biopsy available.
| COPD patients (n = 114) | Controls (n = 37) | |
|---|---|---|
| Males, n (%) | 99 (86.8) | 16 (43.2) |
| Age (years) | 61.6 ± 7.7 | 52.3 ± 5.5 |
| Height (cm) | 175.5 ± 7.8 | 172.8 ± 10 |
| Packyears¶ | 41.8 (31.2 - 54.7) | 25.4 (20.2-35.0) |
| Current smoker, n (%) | 72 (63.2) | 30 (81.1) |
| FEV1/FVC (%) | 49.5 ± 8.8 | 77.2 ± 6.1 |
| FEV1 (L) | 1.8 ± 0.4 | 3.2 ± 0.8 |
| FEV1 % pred.* | 56 ± 10 | 100 ± 14 |
| MRP1 level #, n | 80 | 26 |
Data are presented as mean ± standard deviation or ¶ median (25th - 75th percentile); FEV1 = forced expiratory volume in one second; FEV1/FVC = FEV1/forced vital capacity; * % pred. = percentage of predicted value; # refers to the number of individuals having bronchial biopsies with available MRP1 levels of intensity; MRP1 = multidrug resistance-associated protein-1