Table 2.
Prevalence of MRP1 SNPs in COPD patients and controls.
| COPD patients n = 110 (%) | Controls n = 37 (%) | p value | ||
|---|---|---|---|---|
| rs212093 | AA | 37 (33.9) | 8 (25.0) | 0.55 |
| AG | 50 (45.9) | 18 (56.2) | ||
| GG | 22 (20,2) | 6 (18.8) | ||
| rs4148382 | GG | 83 (76.1) | 29 (82.8) | 0.12 |
| GA | 26 (23.9) | 5 (14.3) | ||
| AA | - | 1 (2.9) | ||
| rs504348 | CC | 78 (72.2) | 22 (71.0) | 0.23 |
| CG | 27 (25.0) | 6 (19.3) | ||
| GG | 3 (2.8) | 3 (9.7) | ||
| rs4781699 | GG | 58 (52.7) | 21 (61.8) | 0.47 |
| GT | 45 (40.9) | 10 (29.4) | ||
| TT | 7 (6.4) | 3 (8.8) | ||
| rs35621 | CC | 89 (80.9) | 30 (85.7) | 0.74 |
| CT | 20 (18.2) | 5 (14.3) | ||
| TT | 1 (0.9) | - | ||
Different numbers for the SNP genotypes are due to missing genotype data
SNP = single nucleotide polymorphism; MRP1 = multidrug resistance-associated protein-1