Table 3.
The number of inflammatory cells in bronchial biopsies and induced sputum of COPD patients
| Bronchial biopsies | Absolute numbers per 0.1 mm2 sub-epithelial area | |
|---|---|---|
| CD3 | 123.5 (69.2 - 182.5) | |
| CD4 | 48.0 (27.7 - 72.0) | |
| CD8 | 21.5 (11.0 - 37.2) | |
| Plasma cells | 8.5 (3.5 - 14.5) | |
| Mast cells | 26.5 (19.0 - 34.5) | |
| Macrophages | 8.5 (4.5 - 13.0) | |
| Neutrophils | 4.0 (2.0 - 8.4) | |
| Eosinophils | 1.5 (0.5 - 4.2) | |
| Induced sputum | Absolute numbers (104/ml) | Percentage (%) |
| Total cell count* | 139.7 (77.9 - 311.3) | |
| Neutrophils | 101.6 (46.8 - 228.5) | 72.8 (59.9 - 81.7) |
| Macrophages | 31.1 (17.9 - 61.1) | 22.1 (14.8 - 33.2) |
| Eosinophils | 1.3 (0.4 - 4.5) | 1.1 (0.3 - 2.2) |
| Lymphocytes | 2.2 (1.1 - 6.8) | 1.7 (1.2 - 2.3) |
| Epithelial cells | 1.4 (0.6 - 3.4) | 1.0 (0.3 - 2.3) |
Data are presented as median (25th - 75th percentile)
*Total cell count refers to the number of non-squamous cells in induced sputum