Figure 9.
Neuroanatomical circuitry altered by post-weaning rearing and handling manipulations alone and in interaction. Thick arrows connect structures of Papez circuitry whereas thin arrows connect input-output loops through the basal ganglia. Key indicates treatment groups that are both color and underline coded to summarize changes in the endocannabinoid system. The key corresponds to the following group comparisons: Group Reared (Handled) vs. All other groups, Handled vs. Non-Handled, Isolation vs. Group Reared, and Isolation (Non-Handled) vs. Group Reared (Non-Handled). AEA, anandamide; 2-AG, 2-arachidonoylglycerol; CBR, cannabinoid receptor.