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. Author manuscript; available in PMC: 2010 Jun 9.
Published in final edited form as: Science. 2003 May 23;300(5623):1291–1295. doi: 10.1126/science.1083022

Fig. 5.

Fig. 5

Fkbp6 colocalizes with Scp1 in synapsed chromosomes of Scp3−/− spermatocytes. (A) Normal SC formation in pachytene oocytes stained with Scp3-rhodamine and FITC-labeled antibodies to Rad51 and Dmc1. Rad51 and Dmc1 foci (arrows) define regions of double-strand breaks. (B) Normal chromosome separation (arrows) in diplotene oocytes stained with Scp3-rhodamine, in a 1-day-old Fkbp6−/− female. (C and D) Expression of Fkbp6 and Scp1 in synapsed regions of Scp3−/− zygotene spermatocytes. (C) Short stretches of FITC-labeled Scp1 mark synapsis between the chromosome cores. (D) Fkbp6 (rhodamine) expression at the residual synapsed regions of Scp3−/− zygotene spermatocytes. Arrows in (C) and (D) show Scp1 and Fkbp6 colocalization.