Table 2. RESULTS OF LOGISTIC REGRESSION ANALYSIS OF NOS2A AND AMD.

(Association between single nucleotide polymorphisms (SNPs) in the NOS2A gene and age-related macular degeneration (AMD) was assessed in 712 AMD cases and 286 controls, adjusting for age and sex. Odds ratios (OR) and 95% confidence intervals (95% CI) indicate the strength of association between AMD and increasing numbers of minor alleles at each SNP. Significant (p<0.05) results are noted in bold.)

SNP	Basepair locationon on chromosome 17	Location in gene (amino acid change if exonic)	OR	95% CI	p-value
rs2255929	23112094	Intron 23	0.82	(0.65, 1.04)	0.099
rs1060826	23113994	Exon 22 (T919T)	1.16	(0.90, 1.49)	0.26
rs2297515	23117460	Intron 19	0.89	(0.64, 1.23)	0.48
rs2297516	23119857	Intron 17	0.82	(0.64, 1.04)	0.10
rs2297518	2312072	Exon16 (S608L)	1.08	(0.80, 1.46)	0.62
rs2248814	23124448	Intron 12	1.17	(0.91, 1.50)	0.22
rs2314810	23128237	Intron 11	1.03	(0.61, 1.76)	0.91
rs1137933	23130059	Exon 10 (D385D)	1.04	(0.78, 1.38)	0.81
rs4795067	23130802	Intron 9	1.04	(0.81, 1.34)	0.75
rs944725	23133698	Intron 6	0.99	(0.79, 1.26),	0.97
rs17722851	23134963	Intron 5	0.75	(0.52, 1.10)	0.14
rs3794764	23135555	Intron 5	0.90	(0.68, 1.20)	0.48
rs16966563	23140076	Exon 4 (P68P)	1.21	(0.56, 2.53)	0.62
rs8072199	23140975	Intron 2	1.30	(1.02, 1.65)	0.035
rs2072324	23141023	Intron 2	0.88	(0.67, 1.18)	0.41
rs3794766	23146048	Intron 2	1.24	(0.92, 1.66)	0.15
rs3730014	23149870	Exon 2 (A31A)	0.59	(0.19, 1.91)	0.38