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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Neuroimmunol. 2010 May 6;223(1-2):104–114. doi: 10.1016/j.jneuroim.2010.03.023

Fig. 2.

Fig. 2

Selected Ab fragments recognize epitopes in middle and/or C-terminus of Aβ1-42. ELISA analysis of binding of selected scFv- and VH-bearing phage clones to synthetic Aβ peptides. NRP - a non-related control peptide. Data are means ± SD of 2 independent experiments. Means denoted with different letters are statistically different (P<0.05). In the same assay BAM90.1 bound to Aβ 12-28 (OD=1.074 ± 0.08), 4G8 bound to Aβ12-28 (OD=1.53 ±0.02) and Aβ17-42 (OD=1.125 ±0.03). Mouse anti-human Aβ1-42 polyclonal antibodies bound to Aβ1-42 and Aβ1-16, OD=1.98 ± 0.04 and OD=1.99 ± 0.05, respectively. Mouse anti-adjuvant serum was used as a negative control and showed OD405 < 0.1.