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Differential expression patterns of proteins between normal subjects and asymptomatic WD patients. C3 (A), FB (B) and α2M (C) were less abundant in WD patients, as established with MS and MS/MS, as well as western blotting using polyclonal antibodies. Following normalization relative to GAPDH, expression of C3, FB and α2M was significantly lower in asymptomatic WD patients than in normal subjects. *p<0.005 and **p<0.001 with Student's t-test.
