Table II.
mAb 4E10-hum | IVIG | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Sia # | S0 | S1 | S2 | Sia # | S0 | S1 | S2 | ||||
p | 0.398 | 0.541 | 0.061 | p | 0.896 | 0.104 | 0.0005 | ||||
S0 | 0.398 | 0.158 | 0.215 | 0.024 | S0 | 0.896 | 0.8028 | 0.0932 | 0.0004 | ||
S1 | 0.541 | 0.215 | 0.293 | 0.033 | S1 | 0.104 | 0.0932 | 0.0108 | 0.0001 | ||
S2 | 0.061 | 0.024 | 0.033 | 0.004 | S2 | 0.0005 | 0.0004 | 0.0001 | 0.0000 | ||
SNA nonbinding (%) | SNA binding (%) | SNA nonbinding (%) | SNA binding (%) | ||||||||
S1-S1 | 29.3 | S1-S1 | 1.08 | ||||||||
S0-S0 | 15.8 | S2-S0 | 4.9 | S0-S0 | 80.3 | S2-S0 | 0.09 | ||||
S1-S0 | 43.1 | S2-S1 | 6.6 | S1-S0 | 18.6 | S2-S1 | 0.01 | ||||
S2-S2 | 3.3 | S2-S2 | 0.01 | ||||||||
Sum | 58.9 | Sum | 44.0 | Sum | 98.9 | Sum | 1.2 |
mAb indicates monoclonal antibody; IVIG, intravenous IgG; SIA, sialic acids; SNA, S. nigra agglutinin.