Table 2.
The various effects of different probiotic strains in allergic diseases are shown from laboratory and clinical studies referred to in the text.
| References | Probiotic strain | Type of allergic disease | Outcome |
|---|---|---|---|
| Atopic dermatitis (eczema) | |||
| Sistek et al.[31] | Lctbs rhamnosus + Bfdbm lactis | Food-sensitized atopic children | ↓ |
| Kalliomäki et al.[45] | Lactobacillus GG | Atopic dermatitis | ↓ |
| Kopp et al.[46] | Lactobacillus GG | Atopic dermatitis | ↔, ↑ |
| Wickens et al.[47] | Lctbs rhamnosus | IgE-associated eczema | ↓ |
| Viljanen et al.[41,48] | LGG | Atopic eczema/dermatitis syndrome | ↓ |
| Rosenfeldt et al.[49] | Lctbs rhamnosus + Lctbs reuteri | Atopic dermatitis | ↓ |
| Kuitunen et al.[50] | Lctbs + Bfdbm + propionibacteria | IgE-associated allergy | ↓ |
| Boyle et al.[54] | Various | Eczema | ↔ |
| Lee et al.[55] | Various | Atopic dermatitis | ↔ |
| Soh et al.[63] | Bfdbm longum + Lctbcs rhamnosus | Eczema and atopic sensitization | ↔ |
| Food allergy and anaphylaxis | |||
| Kim et al.[27] | Lctbs acidophilus + Bfdbm lactis | OVA-induced allergic symptoms | ↓ |
| Isolauri et al.[56] | Bfdbm or Lctbs | Food allergy | ↓ |
| Majamaa et al.[57] | LGG | Food-sensitized eczema | ↓ |
| Shida et al.[60] | VSL#3 + Lctbs casei strain Shirota | Anaphylaxis with food allergy | ↓ |
| Hol et al.[61] | Lctbs casei + Bfdbm Bb-12 | Cow's milk allergy | ↔ |
| Taylor et al.[62] | LGG or Lctbs acidophilus | Cow's milk allergy | ↔, ↑ |
| Allergic rhinitis | |||
| Di Felice et al.[59] | VSL#3 | Allergic rhinitis | ↓ |
| Giovannini et al.[67] | Lctbs casei | Allergic rhinitis | ↓ |
| Morita et al.[69] | LGG + Lctbs gasseri | Allergic rhinitis | ↓ |
| Xiao et al.[71] | Bfdbm longum | Allergic rhinitis; JCP | ↓ |
| Tamura et al.[72] | Lctbs casei strain Shirota | Allergic rhinitis; JCP | ↔ |
| Asthma | |||
| Kruisselbrink et al.[33] | Lctbs plantarum | Dermatophagoides (Der p1) sensitization | ↓ |
| Feleszko et al.[43] | Bfdbm-12 | Airway reactivity | ↓ |
| Blümer et al.[73] | LGG | Allergic asthma | ↓ |
| Repa et al.[74] | Lactococcus lactis + Lctbs plantarum | Birch pollen allergen (Bet v1) sensitization | ↓ |
| Karimi et al.[75] | Lctbs reuteri | Allergic airway inflammation | ↓ |
| Helin et al.[78] | LGG | Pollen allergy | ↔ |
↑: Increase in symptoms or negative effect; ↓: decrease in symptoms or positive effect; ↔: no change in symptoms or no effect; Bfdbm: Bifidobacterium; JCP: Japanese cedar pollinosis; Lctbs: Lactobacillus; LGG: Lctbs rhamnosus GG; VSL#3: probiotic mixture; OVA: ovalbumin.