Table 4. Unadjusted odds ratios for breast cancer by parity, age at first birth, CMV IgG and EBV IgG seroconversion.
Characteristic | Number of cases | Number of controls | Odds ratio for breast cancer | (95% CI) |
---|---|---|---|---|
Nulliparity | ||||
No | 343 | 344 | 1.0 | |
Yes | 56 | 55 | 1.0 | (0.6–1.5) |
Number of children | ||||
None | 56 | 55 | 1.0 | |
1 | 55 | 45 | 1.1 | (0.7–2.0) |
2 | 132 | 124 | 1.1 | (0.7–1.7) |
3 | 103 | 92 | 1.0 | (0.6–1.7) |
4 | 39 | 46 | 0.8 | (0.4–1.5) |
5+ | 14 | 37 | 0.3 | (0.2–0.7) |
Age at first child (for parous women only) (years) a | ||||
0–20 | 63 | 72 | 1.0 | |
21–22 | 68 | 57 | 1.4 | (0.9–2.4) |
23–24 | 47 | 66 | 0.9 | (0.5–1.5) |
25–27 | 59 | 61 | 1.2 | (0.7–2.0) |
28+ | 64 | 45 | 1.8 | (1.0–3.3) |
BMI b | ||||
⩽22 | 83 | 81 | 1.0 | |
21.1–24 | 67 | 63 | 1.1 | (0.6–1.7) |
24.1–26 | 46 | 57 | 0.8 | (0.4–1.3) |
>26 | 81 | 76 | 1.0 | (0.6–1.6) |
Seroconversion for CMV IgG between samples | ||||
No | 388 | 396 | 1.0 | |
Yes | 11 | 3 | 3.7 | (1.0–13.0) |
Seroconversion for CMV IgG between samples in parous women a | ||||
No | 333 | 342 | 1.0 | |
Yes | 10 | 2 | 9.0 | (1.1–71.0) |
Seroconversion for EBV IgG between samples | ||||
No | 397 | 396 | 1.0 | |
Yes | 2 | 3 | 0.7 | (0.1–4.0) |
Abbreviations: BMI=body mass index; CI=confidence interval; CMV=cytomegalovirus; EBV=Epstein–Barr virus; IgG=immunoglobulin G.
Restricted to 301 cases and 301-matched controls with at least one live birth.
Restricted to 277 cases and 277-matched controls with BMI available.