Table A2. Cases of progression to HGD or adenocarcinoma.
| Study ID | Length BE (cm) | DNA ploidy status at baseline | No. of levels DNA ploidy | No. of levels of HGD | Peak DI | Mean CV | Mean n in G1 peak | Peak 5c | DNA ploidy status at 4 months | No. of levels DNA ploidy | Histology | Peak DI | Mean CV | Mean n in G1 peak | Peak 5c | DNA ploidy status at 12 months | No. of levels DNA ploidy | Histology | Peak DI | Mean CV | Mean n in G1 peak | Peak 5c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 6 | Aneuploid | 1 | 1 | 1.51 | 7.2 | 744 | 2.13 | Hypodiploid | 1 | IM | 0.73 | 8 | 777 | 0 | Diploid | 0 | LGD | 1.01 | 6.8 | 852 | 0 |
| 2 | 6 | Aneuploid and tetraploid | 1 | 1 | 1.32/2.02 | 10.9 | 1018 | 0.54 | Aneuploid | 2 | Indefinite | 1.52 | 9.2 | 557 | 0.74 | Aneuploid | 1 | IM | 1.26 | 10.5 | 985 | 0.17 |
| 3 | 7 | Aneuploid, tetraploid | 2 | 1 | 1.76/1.97 | 7.7 | 863 | 0.99 | Aneuploid and tetraploid | 2 | IM | 1.29/1.99 | 10.7 | 363 | 0.23 | Aneuploid and tetraploid | 1 | LGD | 0.5/2.05 | 6.8 | 576 | 0 |
| 4 | 3 | Aneuploid | 1 | 1 | 1.89 | 9.6 | 907 | 1.20 | Aneuploid | 1 | Glandular mucosa | 1.65 | 10.2 | 807 | 0.41 | Aneuploid | 1 | IM | 1.88 | 9.5 | 510 | 0.4 |
| 5 | 11 | Aneuploid and tetraploid | 3 | 2 | 1.48/1.97 | 6.7 | 503 | 1.07 | Aneuploid | 2 | Indefinite | 1.75 | 6.0 | 681 | 0.29 | Not reportable | IM | |||||
| 6 | 3 | Aneuploid | 1 | 1 | 1.89 | 15.1 | 986 | 0.76 | Aneuploid | 2 | IM | 1.63 | 9.0 | 525 | 0.14 | Aneuploid | 1 | Indefinite | 1.38 | 5.0 | 923 | 0.15 |
| 7 | 5 | Aneuploid | 2 | 1 | 1.56 | 9.3 | 725 | 0.37 | Diploid | 0 | Indefinite | 1.00 | 4.4 | 1103 | 0 | Hypodiploid and tetraploid | 1 | IM | 0.50/1.97 | 10.1 | 392 | 0 |
| 8 | 4 | Aneuploid | 1 | 1 | 1.83 | 10.4 | 648 | 0 | Diploid | 0 | Glandular mucosa | 1.01 | 5.9 | 916 | 0 | Aneuploid | 3 | Glandular mucosa | 1.85 | 11.6 | 224 | 1.50 |
| 9 | 13 | Aneuploid and tetraploid | 6 | 3 | 1.74/2.05 | 9.43 | 708 | 1.79 | Aneuploid | 1 | IM | 1.79 | 6.3 | 680 | 0.11 | Aneuploid | 1 | IM | 1.87 | 7.4 | 773 | 0.26 |
| 10 | 3 | Aneuploid | 1 | 1 | 1.31 | 8.6 | 626 | 0.78 | Aneuploid | 3 | Mixed sqaumo-glandular | 1.83 | 6.4 | 745 | 0.21 | Diploid | 0 | Mixed squamo-glandular | 1.00 | 4.6 | 1051 | 0 |
| 11 | 5 | Diploid | 0 | 1 | 0.99 | 5.7 | 888 | 0 | Diploid | 0 | Glandular mucosa | 1.0 | 4.2 | 903 | 0 | Aneuploid | 1 | Glandular mucosa | 1.40 | 13 | 399 | 0.83 |
| 12 | 4 | Diploid | 0 | 1 | 1.01 | 6.7 | 1194 | 0 | Diploid | 0 | IM | 1.02 | 6.3 | 1064 | 0 | Diploid | 0 | IM | 1.03 | 11.1 | 809 | 0 |
| 13 | 2 | Diploid | 0 | 1 | 1.03 | 9.4 | 1274 | 0 | Diploid | 0 | Indefinite | 0.99 | 7.1 | 1059 | 0 | Diploid | 0 | Indefinite | 1.01 | 8.5 | 945 | 0 |
Abbreviations: BE=Barrett's oesophagus; CV=coefficient of variance; DI=DNA index; HGD=high-grade dysplasia; ICDA=image cytometric DNA analysis; LGD=low-grade dysplasia.
Corresponding histology and raw ICDA data at three time points are shown.