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. Author manuscript; available in PMC: 2010 Jun 10.
Published in final edited form as: Infect Disord Drug Targets. 2010 Jun;10(3):226–239. doi: 10.2174/187152610791163336

Fig. 3.

Fig. 3

X-ray structure of PfDHODH. A. Ribbon diagram of an alignment of the structures bound to A77 1726 (tan; pdb 1TV5) and DSM1 (purple; pdb 3I65). B. A77 1726 and DSM1 inhibitor binding sites. Residues marked with * are conserved in human DHODH, while the remainder of the shown residues are variable between Plasmodium and human DHODH. Structures were displayed in PyMol (Delano Scientific)