TABLE 1.
Method | Component | Label Claim (mg/tab) | Amount Found | % Label Claim* | SD | CV |
---|---|---|---|---|---|---|
A | AMLO | 05 | 5.02 | 100.40 | 0.8042 | 0.8012 |
HCTZ | 12.5 | 12.51 | 100.08 | 0.1824 | 0.1823 | |
LOS | 50 | 50.05 | 100.10 | 0.1189 | 0.1188 | |
B | AMLO | 05 | 5.03 | 100.60 | 0.8672 | 0.8620 |
HCTZ | 12.5 | 12.52 | 100.16 | 0.1237 | 0.1235 | |
LOS | 50 | 49.98 | 99.96 | 0.0738 | 0.0738 | |
C | AMLO | 05 | 4.97 | 100.21 | 0.8810 | 0.8791 |
HCTZ | 12.5 | 12.498 | 99.98 | 1.0073 | 1.0075 | |
LOS | 50 | 50.05 | 99.35 | 0.9165 | 0.9225 |
AMLO is amlodipine besilate, LOS is losartan potassium and HCTZ is hydrochlorothiazide
Average of six determinations, SD - Standard Deviation, CV-Coefficient of Variation.