TABLE 2.
Methods | Level of % recovery | % Recovery* | Standard Deviation | Relative standard deviation | ||||||
---|---|---|---|---|---|---|---|---|---|---|
AMLO | HCTZ | LOS | AMLO | HCTZ | LOS | AMLO | HCTZ | LOS | ||
A | 80 | 99.78 | 100.75 | 99.81 | 0.5869 | 0.2758 | 0.0070 | 0.5882 | 0.2737 | 0.0070 |
100 | 101.16 | 100.74 | 99.68 | 0.9122 | 0.3536 | 0.2192 | 0.9017 | 0.3510 | 0.2199 | |
120 | 100.05 | 100.45 | 99.91 | 0.2192 | 0.0212 | 0.0566 | 0.2191 | 0.0211 | 0.0567 | |
B | 80 | 99.35 | 100.14 | 99.97 | 0.1768 | 0.2121 | 0.0778 | 0.1780 | 0.2118 | 0.0778 |
100 | 99.51 | 100.11 | 100.05 | 0.0707 | 0.0919 | 0.0212 | 0.0710 | 0.0918 | 0.0212 | |
120 | 99.33 | 99.92 | 100.05 | 0.1061 | 0.0989 | 0.0070 | 0.1068 | 0.0989 | 0.0070 | |
C | 80 | 100.37 | 100.51 | 100.40 | 0.5515 | 0.2051 | 0.4243 | 0.5495 | 0.2041 | 0.4226 |
100 | 100.71 | 100.58 | 100.07 | 0.0212 | 0.3182 | 0.1485 | 0.0211 | 0.3164 | 0.1484 | |
120 | 99.47 | 99.85 | 99.73 | 0.2263 | 0.0070 | 0.2828 | 0.2275 | 0.0070 | 0.2836 |
AMLO is amlodipine besilate, LOS is losartan potassium and HCTZ is hydrochlorothiazide
Average of three determinations, SD - Standard Deviation, CV-Coefficient of Variation.